The Toxicology Laboratory is concerned with applying "state of the art" techniques to the analysis of body fluids for drugs and chemical poisons. It also has a major interest in the investigation of the relationship between such findings and the signs and symptoms of human toxicity following acute or chronic poisoning.
The laboratory was established in 1997, in the third floor of the out-patient building, Jordan University Hospital, and is relatively well-equipped with modern instruments and systems, which include:
Ø Gas – Chromatography systems (NPD & FID).
Ø High Pressure Liquid Chromatography (HPLC).
Ø Gas – Chromatography / Mass Spectrometer (GC-MS).
Ø Atomic Absorption Spectrometer.
Ø Immunoassay (TDx).
The Laboratory provides a comprehensive analytical service, 24hrs / 7days a week cover for the diagnosis of poisoning. Investigations are carried out on specimens of blood and urine. Screening for an ‘unknown’ drug or poison makes extensive use of both immunoassay and chromatographic techniques for legal confirmation procedures especially in common drugs of abuse. Compounds that are commonly requested by physicians in cases of acute poisoning include analgesics (salicylate, paracetamol), alcohols (ethanol), antidepressants, benzodiazepines, amphetamines, & opiates. Prior consultation is advisable in all cases requiring ‘unknown’ drug / poison screening, particularly when dealing with medico-legal or complex cases.
The Toxicology screening test covers the following:
- Tricyclic Antidepressants
Fulfilling the mission of Jordan University Hospital as an educational hospital and referral medical center; to provide the highest quality of medical services of general & specialized nature; The toxicology laboratory in JUH is the only laboratory in Jordan which provides lead analysis through Atomic Absorption Spectrometer, the most accurate instrument used in qualification & quantitation of heavy metals.
There are a lot of other tests that are carried out through the lab such as; long chain fatty acids & organic acids as partners helping physicians in early diagnosis especially in pediatric cases.
MMA (Methylmalonic Acid); is another test which is carried out using highly accurate procedure which is recommended to diagnose an early or mild vitamin B12 deficiency.
The toxicology lab also offers a comprehensive chance for the MSc students to do their analytical working courses & all aspects of research in a good friendly healthy safe environment, the lab was designed to allow researchers to conduct all of the steps in a study from sample collection to the final stage of analysis results in a single completely contained & regulated facility.